Many low stakes PLO games will play quite similarly to each other (loose passive, pretty straight forward postflop), but every now and then you will play in a very aggressive game that could require you to make some adjustments. Think about the players in your game, especially if they are regs, and how you can best exploit them. If you aren't sure, then adhere to playing a sound strategy that requires you to play solid hands preflop that will play well in MW pots and to a value driven strategy postflop when in fact MW.
Pay close attention to the table for the first hour and begin to make small adjustments as you go. For example, if there is a relentlessly squeeze happy player at the table, then start adjusting by flatting more of the top of your range vs open raises planning on 4-betting/back raising that particular villain.